Thanks for the answers guys, it was my USB mouse which was disconnecting/reconnecting, and thanks Massive I never knew that, now I can finally play PR without shooting unintentionally
I managed to get it working again by following this if anyone is interested:
If you're experiencing mouse lockups or failures, it may be because your computer is automatically turning off the power to a USB Root Hub.
1.Go to your Control Panel > System > Hardware tab > and click on the "Device Manager" button.
2.In the Device Manager window, find the item or items labeled "Universal Serial Bus controllers." Open it, and double-click the first item called "USB Root Hub."
3.In the USB Root Hub Properties dialog, click on the "Power Management" tab.
4."Allow the computer to turn off this device to save power" is checked by default. Uncheck this box, and click "OK."